Phase I Complete. Phase II Fully Funded.

Believe Big is honored to be on the front lines of groundbreaking cancer research. In collaboration with Johns Hopkins University School of Medicine, we are helping advance the first U.S. clinical trial studying intravenous mistletoe, bridging the gap between conventional and complementary medicine in the fight against cancer.

Mistletoe therapy has been used in countries such as Germany and Switzerland for more than 100 years. Bringing it into standard oncology care in the United States, however, requires rigorous clinical research. Each phase builds on the one before it, answering important questions about safety, effectiveness, and its potential impact for patients.

Phase I is complete. The study demonstrated that intravenous mistletoe could be administered safely and showed promising potential to support patients’ quality of life.

Now, we are grateful to share that the Phase II study design has been approved by all collaborating parties and the trial is fully funded through an extraordinary $1 million gift from an anonymous donor who did not want patients to wait any longer.

The study will next move through Clinical Research Committee and Institutional Review Board review. Once those approvals are complete, patient recruitment can begin.

The Journey Continues.

Phase II is a major step toward understanding mistletoe therapy’s effectiveness in a larger group of patients and moving it closer to broader acceptance within oncology care. But this work does not end with Phase II.

We are now raising funds for Phase III—the next critical stage in building the evidence needed to support wider adoption, greater patient access, and the possibility of future insurance coverage.

Unlike conventional treatments backed by major pharmaceutical funding, this research depends on a community of people who believe patients deserve access to more evidence-based treatment options.

That’s where you come in.
Your support helps carry this research forward, from one phase to the next, bringing hope, expanding options, and helping change the future of cancer care.

Download and read the published study here.

To find out more about Mistletoe in science and medicine click here.

Help Move Phase III Forward

As Dr. Diaz shared, completing Phase I was like scoring a touchdown in the Super Bowl, an extraordinary win. Now, with Phase II fully funded and moving through final review, we are looking ahead with purpose and momentum.

Phase III will require another significant investment, and we cannot do it alone.

Your support today helps prepare for the next phase of this groundbreaking research and brings us closer to making mistletoe therapy more widely understood, accepted, and accessible.

Together, we can help move Phase III from vision to reality.

Believe Big only allows 5 percent on overhead of institutional funding.

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FDA Required Disclaimer For Sites That Do Not Endorse Chemotherapy:

This web site is for educational purposes only. It is not intended as a substitute for the diagnosis, treatment and advice of a qualified licensed professional. This site offers people medical information beyond conventional medical options, but in no way should anyone consider that this site represents the “practice of medicine.” This site assumes no responsibility for how this material is used. Also note that this website frequently updates its contents, due to a variety of reasons, therefore, some information may be out of date. The statements regarding medical information beyond conventional treatments for cancer have not been evaluated by the FDA